This is simply the best Super Nintendo available. It's ultra fast and should run at full speed on any Celeron or faster PC.
It also supports Super Nintendo features which are very hard to emulate (and which were unavailable just a while ago), like DSP1 emulation (Mario Kart), SuperFX emulation (StarFox) and now even C4 emulation (Megaman X3)! These features make ZSNES the most compatible Super Nintendo emulator available.

Yet another Game Cube emulator for Windows written using C++.

WhineCube is able to load and execute DOL, ELF or GCM format executables with graphics, pad, DVD and sound emulation.

Requirements:

* Windows XP or later.
* Latest DirectX available.
* A graphics card that support D3DFMT_YUY2 conversion (something like a GeForce 256 or newer).

This emulator does not run any commercial games yet, but you can try a few homebrew such as Pong pong.dol and Wireee wireee.dol.

You can find a compatibility list at the official site. Some of them may require a cache hack.

Since the first version of Visual Boy Advance which lacked some major features (such as an interface), this Gameboy Advance emulator has progressed greatly. I found compatibility to be quite good and many games were playable. Actually I didn't have any problems with every game I tried, though I must admit I didn't test a whole lot of games.
The games ran at full speed (with sound) on my Celeron 900 Mhz., so if you have a similar or faster PC you shouldn't have any problem either. A Pentium III 500 Mhz.

irtuaNES is a relatively new NES emulator from Japanese origin. Fortunately there is an English version of it though. Being newer than other NES emulators doesn't mean it's bad, on the contrary in fact. It supports full CPU and sound emulation.
As with most emulators for Windows, VirtuaNES requires a recent version of DirectX. Being a NES emulator it doesn't require a very fast PC though.

Virtual-E is a Virtual Boy emulator.

UltraHLE 2064 is not just a hack of UltraHLE but a new version based on it's source code. If you want a completely new emulator then it's what you want.
Though the original team is not handling the project the people in charge of it are really tallended and their work can be trusted.

January 28, 1999 is a day which wrote emulation history. UltraHLE was released, the first succesful Nintendo 64 emulator. What many thought of as impossible was achieved by UltraHLE as the first (and only) release was able to properly play many popular titles, including Super Mario 64 and Zelda: Ocarina of Time.

This emulator is out of date specially when compared to emulators like 1964 and Project 64.